Table 1.
Characteristics of patients with ASC.
Total patient number | N = 55 |
---|---|
Male: female | 1:1.4 |
Average age at ASC | 11.8 years (SD ± 3.9) |
Average age at diagnosis of UC | 11.1 years (SD ± 3.7) |
Endoscopic disease location | |
– Left-sided colitis | 2% (n = 1) |
– Extensive colitis | 7% (n = 4) |
– Pancolitis | 91% (n = 50) |
Extra-intestinal manifestations of IBD | 6% (n = 3) |
Treatment at time of admission | (n = 35) |
– Topical/rectal 5-ASA | 24% (n = 13) |
– Oral steroids | 46% (n = 25) |
– Oral 5-ASA | 62% (n = 34) |
PUCAI score: | |
– Day 3 of IVCS | 57 (SD ± 15.1) |
– Day 5 of IVCS | 51 (SD ± 20.2) |
Colectomy | (n = 22) |
– Acute/urgent setting | 20% (n = 11) |
– Elective/semi-elective | 20% (n = 11) |
Remission status at time of maximal follow-up | 56% (n = 29) |
ASC, acute severe ulcerative colitis; IBD, inflammatory bowel disease; IVCS, intravenous corticosteroids; UC, ulcerative colitis.