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. 2017 Dec 21;217(6):897–905. doi: 10.1093/infdis/jix648

Figure 4.

Figure 4.

Predictive value of CXCL10 or CXCL11 protein level for detection of respiratory virus in 151 patient nasopharyngeal swabs (Study 2). A, Correlation between NP swab CXCL10 or CXCL11 protein level and detection of respiratory virus in 151 nasopharyngeal swabs tested for respiratory viruses at Yale-New Haven Hospital in December 2016. CXCL10 and CXCL11 levels were measured using magnetic bead immunoassays. Nucleic acids isolated from the viral transport medium were used to test for viruses not on the original test panel, including 4 CoVs and PIV4. Plots show CXCL11 and CXCL10 levels for 151 samples, sorted by CXCL11 level. Horizontal bar in column labeled virus indicates detection of respiratory virus in the sample; asterisks indicate samples that tested positive for viruses not in the original test panel (Table 1). B, Receiver operating characteristic (ROC) curves for CXCL10 (dashed line) and CXCL11 (solid line) concentrations as predictors of virus detection in this sample set, calculated using SPSS software. C, Viruses detected in the 65/151 virus positive samples in Study 2. Ten distinct viruses were detected, including both influenza A and B and 2 CoV (OC43 and 229E).