Table 1.
Patient Demographics
| Clinical Variables | Control Mothers (n = 15) |
HIV-Infected Mothers (n = 12) |
P Value | |
|---|---|---|---|---|
| Median (75% CI) | Median (75% CI) | |||
| Age, y | 32.6 (30.7–33.2) | 28.5 (28.2–32.4) | .50a | |
| Prepregnancy weight, kg | 64.5b (62.7–66.9) | 68.5 (65.7–74.2) | .41a | |
| Prepregnancy BMI | 22.04b (22.3–24.1) | 23.67 (22.6–26.1) | .79a | |
| Total triglyceridesc, mmol/L | … | 1.80d (1.5–2.1) | ||
| Total cholesterolc, mmol/L | … | 5d (4.6–5.4) | ||
| Glucosec, mmol/L | … | 4.30d (4.2–4.7) | ||
| Ethnicity (white/black/South Asian), No. | 9/4/2 | 3/9/0 | .03e | |
| Gestational diabetes (yes/no), No. | 0/15 | 0/12 | ||
| Viral load, copies/mL | Trimester 1 | … | 528.5 (1269–9084) | |
| Trimester 2 | … | 50 (47.81–281) | ||
| Trimester 3f | … | <50 | ||
| CD4 count, × 106 cells/L | Trimester 1 | … | 455 (465.5–594.5) | |
| Trimester 2 | … | 520 (511.4–650.6) | ||
| Trimester 3 | … | 700 (616.5–792.5) | ||
| Control Infants (n = 15) |
cART/HIV-1–Exposed Infants (n = 12) | |||
| Gestation period, wk | 40 (37.63–39.97) | 39.25 (38.74–39.82) | .57a | |
| Birth weight, g | 3380 (3128–3494) | 3085 (3009–3472) | .34a | |
| Apgar score | (5 min) | 10 (9.5–9.9) | 10 (9.1–9.9) | .44a |
| Mode of delivery (vaginal/cesarean), No. | 14/1 | 8/4 | .14e | |
| Gender (male/female), No. | 8/7 | 7/5 | .55e | |
Abbreviations: BMI, body mass index; CI, confidence interval.
aMann–Whitney U test.
bOne mising value.
cMeasured at the end of the second trimester.
dTwo missing values.
eFisher exact test.
fAll mothers were below the limit of detection.