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. 2018 Feb 2;8(2):83. doi: 10.3390/nano8020083

Table 1.

The IC50 values of GA, Doxorubicin and Fe3O4-PEG-GA on cancer cell lines.

Cancer Cell Lines IC50 (μg/mL) * Effective IC50 (μg/mL) **
GA Fe3O4-PEG-GA Doxorubicin Fe3O4-PEG-GA
HT29 14.52 ± 0.94 4.85 ± 0.33 0.33 ± 0.03 1.70
MCF-7 21.35 ± 4.14 7.28 ± 0.64 0.05 ± 0.01 2.55
A549 56.49 ± 4.31 37.49 ± 1.42 0.58 ± 0.01 13.1

* Values are expressed as the mean ± standard deviation of 3 replicates. The IC50 value is defined as the concentration of drug needed for 50% cell inhibition; ** Values of actual IC50 that were calculated based on 35% GA loading in the nanocomposite.