Table 1.
Cancer Cell Lines | IC50 (μg/mL) * | Effective IC50 (μg/mL) ** | ||
---|---|---|---|---|
GA | Fe3O4-PEG-GA | Doxorubicin | Fe3O4-PEG-GA | |
HT29 | 14.52 ± 0.94 | 4.85 ± 0.33 | 0.33 ± 0.03 | 1.70 |
MCF-7 | 21.35 ± 4.14 | 7.28 ± 0.64 | 0.05 ± 0.01 | 2.55 |
A549 | 56.49 ± 4.31 | 37.49 ± 1.42 | 0.58 ± 0.01 | 13.1 |
* Values are expressed as the mean ± standard deviation of 3 replicates. The IC50 value is defined as the concentration of drug needed for 50% cell inhibition; ** Values of actual IC50 that were calculated based on 35% GA loading in the nanocomposite.