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. 2018 Feb 3;8(2):85. doi: 10.3390/nano8020085

Figure 9.

Figure 9

Antitumor ability of ART-loaded d-MOFs nanospheres in HeLa xenograft mice models. (a) The excised tumors from different mice groups treated with saline, NIR irradiation, free ART, d-MOFs@ART, d-MOFs + NIR, d-MOFs + ART + NIR (non-encapsulated) and d-MOFs@ART + NIR at 32nd day; (b) Tumor growth curves of mice after various treatments (mean ± SD., n = 5, * p < 0.05, ** p < 0.01); (c) Tumor inhibition ratio of the NIR irradiation, free ART, d-MOFs@ART and d-MOFs + NIR group and d-MOFs@ART + NIR tumor inhibition ratio of chemo-thermal therapy (mean ± SD., n = 5, * p < 0.05, ** p < 0.01); (d) Body weights of mice for varied time periods for 32 days after various treatments. ART = artemisinin. d-MOFs = dual metal organic frameworks. Reproduced with permission from [107]. Elsevier, 2016.