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. 2018 Feb 22;8(2):121. doi: 10.3390/nano8020121

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Regrowth curves and (B) relative weight curves of A431 tumors in nude mice submitted to photodynamic therapy (PDT) treatment. The data are presented as the means ± standard deviation. * Significantly different compared with the control or non-tumor targeting PDT-treated groups (p < 0.05). Hematoxylin and eosin (H&E) and proliferating cell nuclear antigen (PCNA) staining of A431 xenograft tumors treated with phosphate-buffered saline (PBS) or micellar Ce6 with irradiation. (C,G) Control. (D,H) Ce6-PDT; (E,I) Ce6-PDT/PM; (F,J) C225-Ce6/PM-PDT. (C–F): H&E staining. (G–J): PCNA staining.