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. 2018 Feb 24;8(2):125. doi: 10.3390/nano8020125

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Murine macrophage, RAW 264.7 cells after treatment with GONPs. Parameters assessed (a) cell viability; (b) nitric oxide production; (c) Interleukin 6 (IL-6) production; (d) Macrophage inflammatory protein 1 alpha (MIP-1α) levels. Positive control not represented (803.85 ± 353.70 ng/mL MIP-1α); (e) MIP-1β levels. Positive control not represented (1127.19 ± 468.69 ng/mL MIP-1β); and (f) MIP-2 levels. Positive control not represented (307.39 ± 171.86 ng/mL MIP-2). Data represents mean ± SD with n = 9. Bars marked with symbols indicate significant difference to control (p < 0.01). Significance demarcated by: *—significantly different compared to negative control (p < 0.001), ^#—significantly different compared to positive control (p ≤ 0.005).