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. 2018 Feb 24;8(2):125. doi: 10.3390/nano8020125

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effect of graphene oxide nanoparticles (GONPs) on RAW 264.7 cells. Cells were incubated with (a) media only (negative control); (b) media in the presence of LPS and (c) 15.6 μg/mL GONPs in the absence of a mitogen. Supernatants were probed using the proteome profiler array as described in methods. Cytokines/chemokines that were detected were allocated numbers: 1, 3 and 16 are reference spots; 2-IP-10; 4-G-CSF; 5-TNF-α; 6-GM-CSF; 7-IL-6; 8-JE; 9-sICAM-1; 10-MIP-1α; 11-MIP-1β; 12-IL-1β; 13-MIP-2; 14-IL-1ra; 15-RANTES; 17-IL-27; 18-SDF-1.