. 2017 Mar 3;215(8):1275–1284. doi: 10.1093/infdis/jix120

Table 3.

Single-Dose Fecal Concentrations of Bumped-Kinase Inhibitors 1294 and 1534 in Uninfected Adult Mice, Compared With the Fifth-Dose Fecal Concentrations in Infected Adult Mice

Infection Status, Dose	Concentration, µM
Infection Status, Dose	1294	1534
Uninfected, single dose^a
25 mg/kg orally	4.4	10.1
60 mg/kg subcutaneously	0.92	0.44
Infected, fifth dose^b
60 mg/kg orally	4.1	17.8
60 mg/kg subcutaneously	1.1	4.7

^aConcentration (weight/volume) in pooled fecal specimens from adult uninfected mice given a single oral or subcutaneous dose.

^bConcentration (weight/volume) in pooled fecal specimens from interferon γ knockout mice infected with Cryptosporidium parvum after the fifth oral or subcutaneous dose.