Table 1.
Demographic and Clinical Information and Human Immunodeficiency Virus (HIV)/Kaposi’s Sarcoma–Associated Herpesvirus (KSHV) Status Among Study Patients
| Subject | Age, y | Sex | Cause of Deatha | Received ART | Serostatusb | KSHV-Specific PCR/Southern Blot Result, by Brain Regionb | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HIV | KSHV | FL | PL | TL | OL | Hip | Cer | BG | |||||
| 92 | 32 | Male | Tuberculosis | No | + | + | − | − | − | + | + | + | − |
| 111 | 19 | Male | RVD and anemia | Yes | + | + | − | − | − | − | − | − | − |
| 116 | 44 | Male | Meningitis, R/0 tuberculosis | No | + | + | + | + | + | + | + | + | + |
| 221 | 26 | Female | CNS OI, malaria, metabolic derangements | Yes | + | + | − | − | − | − | − | − | − |
| 228 | 34 | Female | RVD, tuberculosis-associated meningitis | No | + | + | − | − | − | − | − | − | − |
| 230 | 30 | Male | Hemiplegia, RVD, possible toxoplasmosis | No | + | + | − | − | + | − | − | − | − |
| 283 | 34 | Female | RVD, tuberculosis | Yes | + | + | − | − | − | − | − | − | − |
| 315 | 24 | Male | RVD, meningitis | No | + | + | − | − | − | − | − | − | − |
| 320 | 40 | Female | Disseminated tuberculosis | Unknown | + | + | − | − | − | − | − | − | − |
| 321 | 35 | Female | Peripheral neuropathy and disseminated tuberculosis | Unknown | + | + | − | − | − | − | + | − | − |
| 231 | 34 | Male | RVD, toxic epidermal necrolysis | Yes | + | − | − | − | − | − | − | − | − |
| 001 | 47 | Male | Homicide/murder | No | − | − | − | − | − | − | − | − | − |
Abbreviations: ART, antiretroviral therapy; CNS, central nervous system; BG, basal ganglia; Cer, cerebellum; FL, frontal lobe; Hip, hippocampus; OI, opportunistic infection; OL, occipital lobe; PCR, polymerase chain reaction; PL, parietal lobe; RVD, retroviral disease; TL, temporal lobe.
aBased on report from University Teaching Hospital (Lusaka).
bA plus sign indicates seropositivity for HIV/KSHV antibody or a positive result of KSHV-specific PCR and Southern blot in various brain tissue specimens, and a minus sign indicates seronegativity for HIV/KSHV antibody or a negative result of KSHV-specific PCR and Southern blot in various brain tissue specimens.