Table 1.

Single-Nucleotide Polymorphisms Associated With Variations in Rubella-Specific Interleukin 6 Secretion in Subjects of European Ancestry

SNP	Chromosome	Gene	Reference Base	Substituted Base	Typea	P Value
rs4986811 b	11	WT1	T	G	Intron	1.22 × 10–8
rs5030172 b	11	WT1	G	C	Intron	2.07 × 10–8
rs5030157 b	11	WT1	C	T	Intron	2.18 × 10–8
rs5030166 b	11	WT1	G	T	Intron	3.69 × 10–8
rs11031780b,c	11	WT1	C	G	Intron	7.00 × 10–8
rs7936152b	11	WT1	G	A	Intron	7.17 × 10–8
rs11031781b	11	WT1	G	A	Intron	7.18 × 10–8
rs11031779b,c	11	WT1	C	T	Intron	7.68 × 10–8
rs2234582b	11	WT1	C	A	Synonymous	1.49 × 10–7
rs72893517b	11	WT1	G	C	Intron	2.08 × 10–7
rs12293603b	11	WT1	C	A	Intron	5.13 × 10–7
rs5030180b	11	WT1	G	A	Intron	7.06 × 10–7

Abbreviations: SNP, single-nucleotide polymorphism.

Bold indicates P ≤ 5 × 10⁻⁸.

^aPredicted function.

^bIndicates an SNP identified in a WT1 transcript variant known to be a target of nonsense mediated decay (NMD).

^cIndicates a predicted transcription factor binding site (Ensembl).