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. 2017 Jul 1;216(Suppl 1):S168–S175. doi: 10.1093/infdis/jix128

Table 1.

Serotype-Specific Model Inputsa

Model Input Source(s) Serotype 1 Estimate Serotype 2 Estimate Serotype 3 Estimate
Basic reproduction number (R0) for WPV or fully reverted VDPV, relative to serotype 1 [7, 37] 1 (reference) 0.9 0.75
Relative R0 of OPV parent strain to WPV or VDPV [7] 0.37 0.55 0.25
Average time (days) to revert from OPV to fully reverted VDPV [37] 620.5 408 620.5
Average paralysis-to-infection ratio for fully susceptible individuals [7]
WPV 1/200 1/2000 1/1000
OPV 7.4 × 10–8 6.2 × 10–7 1.3 × 10–6
Average per-dose OPV take rate for population modeled in Figure 2 [21] 0.42 (bOPV) 0.60 (tOPV) 0.42 (bOPV)

Abbreviations: bOPV, bivalent oral poliovirus vaccine; OPV, oral poliovirus vaccine; tOPV, trivalent oral poliovirus vaccine; VDPV, vaccine-derived poliovirus; WPV, wild poliovirus.

aExcluding small serotype differences in characterization of immunity states [7].