Figure 2.
Colonization and infection dynamics of Enterococcus faecalis in wounds. Wounds were harvested at the indicated time points postinoculation and the colony forming units (CFU) enumerated. Mice were inoculated with (A) 102 CFU of OG1RF, (B) 106 CFU of OG1RF, (C) 102 CFU of V583, or (D) 106 CFU of V583. Each dot represents 1 mouse, and the solid horizontal lines indicate the median, N (biological replicates) = 2, n (technical replicates) = ≥5. Statistical analysis was performed using Kruskall–Wallis test with Dunn’s post-test to correct for multiple comparisons. * P < .05, ** P < .01. Abbreviations: hpi, hours postinfection; dpi, days postinfection.