Figure 3.

Multiple peptide resistance factor (MprF) contributes to fitness during Enterococcus faecalis wound infection. Wounds were infected with a 1:1 ratio of E faecalis strains OG1X:wild type OG1RF or OG1X:OG1RF ΔmprF1/2, at 10⁶ colony forming units per inoculum, harvested at 3 days postinfection, and the recovered bacteria enumerated on selective media for each strain. Each dot represents 1 mouse, and the solid horizontal lines indicate the median, N = 3, n = 5. Statistical analysis was performed using Mann–Whitney U test. **** P < .0001. Abbreviations: N, biological replicates: n, technical replicates