Sorbitol metabolism-associated pathways in (A) fruits and (B) leaves of climacteric Santa Rosa (SR; black bars) and non-climacteric Sweet Miriam (SM; white bars) throughout development [S2 (pit hardening)] and ripening [S3/S4 (mature), S4-I (commercial harvest), S4-II (fully ripe)] stages on the tree. Sugar contents are presented in graphs framed by dashed lines and are expressed as milligrams per gram of dry weight (D.W.). Enzyme activities are expressed as moles of metabolite generated/consumed per milligram of protein per unit of time. Values are presented as means ±SE (n=6). The data were analyzed using two-way ANOVA followed by Tukey’s test. Different letters indicate significant differences (P<0.05). S6PDH, sorbitol-6-phosphate dehydrogenase; NAD+-SDH, NAD+-dependent sorbitol dehydrogenase; SOX, sorbitol oxidase; HK, hexokinase; G6P, glucose-6-phosphate; Sor, sorbitol; Fru, fructose; Glu, glucose.