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. 2018 Mar 15;13(3):e0192664. doi: 10.1371/journal.pone.0192664

Table 6. ROC curves features of the 14 markers increased in active TB.

ROC curve of non TB vs Active TB (Ag-Nil)
Area under the ROC curve Std. Error 95% confidence interval p value cutoff Sensitivity% 95% CI Specificity% 95% CI Likelihood ratio
IL2 0.7778 0.09485 0.5918 to 0.9637 0.02539 > 42.13 81.48 61.92% to 93.70% 95 75.13% to 99.87% 16.3
IP10 0.7942 0.07397 0.6492 to 0.9393 0.000704 > 6557 80.77 60.65% to 93.45% 85 62.11% to 96.79% 5.385
IFN-γ 0.8269 0.06213 0.7051 to 0.9487 0.000148 > 57.38 70.37 49.82% to 86.25% 90 68.30% to 98.77% 7.037
MIG 0.8944 0.07156 0.7542 to 1.035 0.000669 > 6.456 94.44 72.71% to 99.86% 90 55.50% to 99.75% 9.444
SCF 0.9353 0.05365 0.8301 to 1.040 0.000205 > 39.37 94.12 71.31% to 99.85% 90 55.50% to 99.75% 9.412
b-NGF 0.8765 0.06869 0.7418 to 1.011 0.00132 > 1.965 70.59 44.04% to 89.69% 90 55.50% to 99.75% 7.059
IL12-p40 0.8944 0.06315 0.7706 to 1.018 0.000669 > 86.37 83.33 58.58% to 96.42% 90 55.50% to 99.75% 8.333
TRAIL 0.9028 0.06148 0.7823 to 1.023 0.000513 > 34.01 83.33 58.58% to 96.42% 90 55.50% to 99.75% 8.333
IL2 Ra 0.8333 0.08273 0.6711 to 0.9955 0.005499 > 21.69 55.56 30.76% to 78.47% 88.89 51.75% to 99.72% 5
MIF 0.8706 0.06827 0.7367 to 1.004 0.00157 < 110.1 76.47 50.10% to 93.19% 90 55.50% to 99.75% 7.647
TNF-β 0.8667 0.06776 0.7338 to 0.9995 0.001563 > 5.405 72.22 46.52% to 90.31% 90 55.50% to 99.75% 7.222
IL3 0.8 0.08311 0.6371 to 0.9629 0.009651 > 155.0 66.67 40.99% to 86.66% 90 55.50% to 99.75% 6.667
IFN-α 0.8667 0.0723 0.7249 to 1.008 0.001563 > 13.35 83.33 58.58% to 96.42% 90 55.50% to 99.75% 8.333
LIF 0.7778 0.08809 0.6051 to 0.9505 0.01655 > 25.70 66.67 40.99% to 86.66% 90 55.50% to 99.75% 6.667