Table 7. General discriminant analysis of different biomarker combinations.
| GDA | Wilks' lambda | Active TB vs LTBI |
Active TB vs Non TB |
LTBI vs Non TB |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Seven biomarkers | Active TB (%) |
LTBI (%) |
Non TB (%) |
Total (%) |
F | p | F | p | F | p | |
| MCP-1 [NIL], LIF [NIL], IL2, IFN-γ, MIF, TRAIL, IL2Ra |
88.89 | 82.35 | 90.00 | 86.67 | 0.242 | 5.12 | 0.0004 | 6.15 | <0.0001 | 4.83 | 0.0007 |
| PDGF [NIL], LIF [NIL], IL2, IFN-γ, MIF, IL12-p40, IL2Ra |
83.33 | 76.47 | 100.00 | 84.44 | 0.247 | 4.82 | 0.0007 | 6.62 | <0.0001 | 4.81 | 0.0007 |
| PDGF [NIL], LIF [NIL], IL2, IFN-γ, MIF, TRAIL, IL2Ra |
77.78 | 64.71 | 100.00 | 77.78 | 0.243 | 4.71 | 0.0008 | 6.43 | <0.0001 | 4.78 | 0.0007 |
| Sixbiomarkers | |||||||||||
| MCP-1 [NIL], LIF [NIL], IL2, IFN-γ, MIF, TRAIL |
88.89 | 70.59 | 90.00 | 82.22 | 0.280 | 6.06 | 0.0002 | 6.31 | 0.0001 | 4.20 | 0.0026 |
| MCP-1 [NIL], LIF [NIL], IL2, IFN-γ, MIF, L12-p40 |
83.33 | 70.59 | 80.00 | 77.78 | 0.279 | 5.71 | 0.0003 | 6.42 | 0.0001 | 4.52 | 0.0016 |
| PDGF [NIL], LIF [NIL], IL2, IFN-γ, MIF, IL12-p40 |
77.78 | 64.71 | 100.00 | 77.78 | 0.278 | 5.55 | 0.0004 | 6.91 | <0.0001 | 4.43 | 0.0018 |