Fig 1. HRs and 95% CIs for all-cause mortality according to spline eGFR and ACR in urban China and the US.

HRs and 95% CIs (area between dashed lines) according to eGFR and ACR in China (A, C) and US (B, D). The associations were adjusted for age, sex, education level, smoking, history of cardiovascular disease, hypertension, diabetes, body mass index, and ln(ACR)(when testing for spline eGFR)/eGFR(when testing for spline ACR). The reference (diamond) was eGFR 90 mL/min/1·73 m² and ACR 5 mg/g, respectively. Triangles represent statistically significant and circles represent not significant. Abbreviation: HR = Hazard ratio, CI = Confidence interval, eGFR = Estimated glomerular filtration rate, ACR = Albumin-to-creatinine ratio.