Table 1. Viral titers in brains of mice engorged upon by ZIKV-infected mosquitoes.
| Mosquito Strain | Days after infection (Mosquito) | Infection Type (Mosquito) |
Day of death (Mouse) |
Viral titer in brain (PFU/g) |
|---|---|---|---|---|
| HCM | 10 | Oral | 11 | 1.4 x 108 |
| ORL | 7 | Injection | 12 | 1.0 x 108 |
| ORL | 7 | Injection | 21 | 5.0 x 102 |
| ORL | 10 | Injection | 10 | 1.8 x 108 |
| ORL | 10 | Injection | 10 | 1.8 x 108 |
| ORL | 10 | Injection | 23 | 2.4 x 107 |
| PAT | 7 | Injection | 9 | 3.3 x 108 |
| PAT | 7 | Injection | 13 | 2.1 x 108 |
| PAT | 7 | Injection | 25 | 6.5 x 106 |
| PAT | 10 | Injection | 10 | 1.1 x 108 |
| PAT | 10 | Injection | 14 | 1.6 x 107 |
| HCM | 7 | Injection | 27 | 3.0 x 104 |
| HCM | 10 | Injection | 14 | 2.7 x 107 |
| HCM | 10 | Injection | 26 | 1.0 x 106 |
| HCM | 10 | Injection | 27 | 9.7 x 104 |
ORL, PAT or HCM strains were infected with ZIKV, either orally or by intrathoracic injection, for 7 or 10 days before being allowed to take a blood meal on naïve AG129 mice. When mice died, brains were collected, and plaque assays were performed on the samples.