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. 2018 Mar 5;12(3):e0006251. doi: 10.1371/journal.pntd.0006251

Fig 1. Effect of CsTPs on expressions of co-stimulatory molecules on LPS-induced BMDCs.

Fig 1

(A) Representative images of co-stimulatory molecules MHC-II, CD80 and CD86 on BMDCs detected by FACS. one marrow cells from BALB/c mice were cultured with IL-4 and GM-CSF. At Day 7, immature BMDCs were harvested and 1 × 106/ml cells were treated with 20, 40 or 80 μg/ml CsTPs or 0.5 μg/ml Alb (control protein) in the presence of 1μg/ml LPS as a maturation factor or medium alone for 24 h. The maturation phenotype of CD11c+ BMDCs were assessed by FACS for the expressions of co-stimulatory molecules MHC-II, CD80 and CD86. (B) Statistical analysis of expression percentages of the surface markers on CD11c+ BMDCs. Data are shown as mean ± SD of three independent experiments. Statistical significance was analyzed by one-sided paired Student’s t-test (*, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001 vs. LPS group).