Table 3. Distribution of Lagos bat virus antigen in the brains of experimentally infected bats.
| Inoculum Group | Bat no. | Days to death | Category of antigen-positive neurons per brain section | Average category of antigen-positive neurons per brain | Average category of antigen-positive neurons per brain, per group | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Aa | B | C | D | E | F | |||||
| Senegal | 13 | 4 | 1b | 1 | 2 | 1 | 3 | 3 | 2 | |
| 5 | 6 | 2 | 1 | 2 | 1 | 1 | 3 | 2 | ||
| 6 | 5 | 3 | 4 | 3 | 3 | 3 | 3 | 3 | 2 | |
| Nigeria | 7 | 8 | 3 | 2 | 1 | 1 | 4 | 2 | 2 | |
| 8 | 8 | 1 | 1 | 2 | 1 | 3 | 2 | 2 | ||
| 9 | 8 | 4 | 3 | 3 | 3 | 2 | 2 | 3 | 2 | |
| Ghana | 10 | 5 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | |
| 11 | 5 | 1 | 1 | 1 | 1 | 2 | 3 | 2 | ||
| 12 | 6 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1* | |
| Average | 2 | 2 | 2 | 1 | 2 | 3 | ||||
a Brain section A corresponds to the most rostral part, section F to the most caudal part of the brain.
b Category 1: 0–25% of the neurons antigen positive in 10, 40X objective fields arbitrarily selected in this brain section, 2: 26–50%, 3: 51–75%, 4:76–100%.
* Significantly lower than the average score of Nigeria and Senegal groups (p = 0.004, paired t-test).