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. 2018 Mar 5;12(3):e0006311. doi: 10.1371/journal.pntd.0006311

Table 4. Neuronal routes different Lagos bat viruses travelled from the intracranial inoculation site to the periphery.

LBV strain(s) Peripheral location Deduced route for centrifugal spread of LBVs from intracranial inoculation site to periphery
Origin in CNS Route (nerves & ganglia) Characteristics of neuronal route
Specific nucleus General location of nucleus in CNS Number of synapses to pass Division of nervous system involved
Ghana Tongue ganglion Salivatory Motor medulla Chorda tympani and glossopharyngeal nerves 1 Parasympathetic motor
Ghana Otic ganglion (salivary gland) Inferior salivatory Motor medulla Chorda tympani and glossopharyngeal nerves 1 Parasympathetic motor
Ghana, Senegal Cardiac plexi at base of hearta Dorsal motor nucleus of vagus nerve Motor medulla Vagus nerve 1 Parasympathetic motor
Cranial four to five segments thoracic spinal cord Spinal cord Cervical paravertebral sympathetic trunk and postganglionic fibers 2 Sympathetic motor
Ghana Myenteric plexi of duodenum and jejunuma Dorsal motor nucleus of vagus nerve Motor medulla Vagus nerve 1 Parasympathetic motor
Dorsal horn spinal cord Spinal cord Splanchnic nerve, celiac ganglion, and postganglionic fibers 2 Sympathetic motor
Ghana, Senegal Taste buds on tongue Solitary tract Sensory medulla Geniculate, petrosal and nodosal ganglia 2 Special sensory

a More than one route possible because of innervation of the nervous plexi by both parasympathetic and sympathetic nervous system.