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. 2018 Mar 5;14(3):e1006806. doi: 10.1371/journal.ppat.1006806

Fig 4. Deletion of A20 enhances the proinflammatory effects of IL-17A.

Fig 4

Gene expression of (A) Lcn2, (B) Cxcl1, (C) Cxcl2, (D) Muc1 by qPCR of organoid cultures after 24 hours of 4OHT treatment and/or a 12 hour stimulation with recombinant IL-17A. Cre+ or Cre- conditions were tested separately by ANOVA. Pairwise comparisons were completed post-hoc using t-tests and correcting for multiple comparisons by the Scheffe method (see also S2 Table). Stars above each column indicate statistical significance relative to the media condition of the same organoid line (Cre+ or Cre-) by a t-test. Bars with stars indicate statistically significant differences between the two indicated conditions. **P≤0.01, ***P≤0.001, ****P≤0.0001.