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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Adv Mater. 2018 Jan 8;30(7):10.1002/adma.201703178. doi: 10.1002/adma.201703178

Figure 3.

Figure 3

Different profiles of IL-2 administration to CD8+ T-cells impacts differentiation of them to central or effector memory cells. a) Flow cytometric analysis of CD44 and CD62L coexpression at two cells per particle a,i–iv), one particle per cell c,i–iv), and two particles per cell e,i–iv). i) noncoated particles or ii) coated particles in each set (day 12). Percentage of effector cells (CD44+CD62L−) in each case iii) or memory (CD44+CD62L+) phenotype iv). Histograms of CCR7 expression of memory subset of cells,b),d), and f), when cells are treated with noncoated particles i) or coated ii) particles and their MFIs iii) at day 12. g,h) Flow cytometric analysis of granzyme B (i) and perforin (ii) expressions as a function of treatment modality and time. The presented data are expressed as average ± SD. The results were statistically analyzed using unpaired t-tests.