Table 1.
HC (N = 17) | AD (N = 26) | DLB (N = 25) | PDD (N = 21) | p-value | |||||
---|---|---|---|---|---|---|---|---|---|
Age | 76.18 | ±5.65 | 76.46 | ±7.83 | 75.8 | ±6.5 | 73.29 | ±5.842 | F(3,85) = 1.03, p-value = 0.380Т |
Male/Female | 10/7 | 18/8 | 20/5 | 19/2 | Χ2(3, N = 89) = 5.89, p-value = 0.117ǂ | ||||
MMSE | 29.12 | ±0.857 | 20.08 | ±4.279 | 22.64 | ±4.3 | 22.71 | ±4.85 | F(2,69) = 2.81; p-value = 0.067* |
CAMCOG total | 96.47 | ±3.69 | 66.54 | ±16.46 | 76.08 | ±12.92 | 73.38 | ±13.88 | F(2,69) = 2.89; p-value = 0.063* |
CAMCOG executive | 22.71 | ±2.25 | 14.46 | ±5.49 | 13.12 | ±5.03 | 12.9 | ±2.86 | F(2,69) = 0.79; p-value = 0.457* |
CAMCOG memory | 23.47 | ±2.035 | 10.88 | ±5.1 | 18.04 | ±4.9 | 17.48 | ±5.05 | F(2,69) = 15.5; p-value < 0.001* |
CAMCOG attention | 6.76 | ±0.562 | 3.81 | ±2.514 | 4.4 | ±2.27 | 4.19 | ±1.721 | F(2,69) = 0.465; p-value = 0.63* |
NPI hall | 0 | 0 | 0.04 | ±0.2 | 1.76 | ±1.86 | 2.57 | ±2.29 | F(2,68) = 14.1; p-value < 0.001* |
CAF total | 0 | 0 | 0.6 | ±1.52 | 3.92 | ±4.142 | 6.63 | ±4.271 | t(42) = 2.12, p-value = 0.03╤ |
Animal Categorical fluency | 20.71 | ±5.71 | 11.15 | ±5.25 | 11.16 | ±3.88 | 11.33 | ±4.14 | F(2,69) = 0.011; p-value = 0.989* |
UPDRS III | 1.24 | ±1.522 | 2.28 | ±1.929 | 15.52 | ±8.2 | 25.57 | ±7.018 | t(44) = 4.42, p-value < 0.001╤ |
Angle discrimination | 19.63 | ±0.88 | 18.24 | ±3.72 | 16.17 | ±4.85 | 16.55 | ±4.99 | H(2) = 4.1, p-value = 0.129ǂ |
FAS Verbal fluency | 45.12 | ±16.53 | 25.96 | ±16.14 | 19.68 | ±12 | 20.81 | ±13.7 | H(2) = 1.94, p-value = 0.378ǂ |
LEDD | 0 | 0 | 0 | 0 | 164.88 | ±231.6 | 818.23 | ±381.3 | t(44) = 7.15, p-value < 0.001╤ |
ACheI (yes/no) | 0/17 | 24/2 | 23/2 | 16/4† | Χ2(2, N = 71) = 2.13, p-value = 0.346 | ||||
Years since diagnosis | 0 | 0 | 1.77 | ±1.13 | 0.87 | ±0.63 | 1.41 | ±1.91 | H(2) = 10.9, p-value = 0.004ǂ |
*ANOVA three groups (AD, DLB, PDD);
ТANOVA four groups;
ǂχ2 test four groups.
ǂUnpaired t-test (DLB vs PDD);
‡Kruskal-Wallis three groups (AD, DLB, PDD).
†One PDD patient was on Memantine.