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. 2018 Mar 15;8:4627. doi: 10.1038/s41598-018-22799-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Regeneration of TE artery in CG and NCG. (A) H&E (bar: 200 μm), Masson’s trichrome (bar: 200 μm) and Intima of TE artery (SEM, bar: 50 μm in CG, bar: 100 μm in NCG). (B) Endothelial layer, smooth muscle cell layer and vascularization within the adventitia of TE arteries (IHC, bar: 100 μm). (C) Quantification, (1) Continuity of endothelial layer, (2) Quantification of SMCs of TE artery, (3) Quantification of vessels formation in the adventitia of TE artery. (D) Colocalization of MSCs and ECs (I green indicated MSCs, II red showed ECs, III merge), (1) Intima of TE artery in CG, (2) Intima of TE artery in NCG, Endothelium (White arrow), SMC (Black arrow), blood vessels of adventitia (Red arrow).