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. 2018 Mar 9;9:459. doi: 10.3389/fimmu.2018.00459

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Copyright © 2018 Genoula, Marín Franco, Dupont, Kviatcovsky, Milillo, Schierloh, Moraña, Poggi, Palmero, Mata-Espinosa, González-Domínguez, León Contreras, Barrionuevo, Rearte, Córdoba Moreno, Fontanals, Crotta Asis, Gago, Cougoule, Neyrolles, Maridonneau-Parini, Sánchez-Torres, Hernández-Pando, Vérollet, Lugo-Villarino, Sasiain and Balboa.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cholesterol levels and foamy macrophages (FM) are associated with interleukin-10 (IL-10) amounts present in tuberculous pleural effusion (TB-PE). (A,B) Correlation analysis between the levels of IL-10 and (A) the cholesterol content (n = 38) or (B) the number of lipid-laden CD14⁺ cells within the pleural fluids mononuclear cells (PFMC) (n = 12) found in individual preparations of TB-PE. In B log-10 scale for both axes is used. Linear regression lines are shown. Spearman’s rank test. (C) Representative image of ORO staining of CD14⁺ cells isolated from paired peripheral blood mononuclear cells (PBMC) and PFMC is shown (40× magnification).