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. 2018 Mar 9;12:11. doi: 10.3389/fninf.2018.00011

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Copyright © 2018 Hsu, Hou, Johnson, Wu, Noll, Prabhu, Ferguson, Kumar, Schomer, Hazle, Chen and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The GUI of the CVR Mapping module displayed with processing and visualization for Patient #1. This window consists of the imaging data input panel (Upper Left), breath-hold paradigm setting (Middle Left), preprocessing selection (Upper Right), visualization widget (Middle), and two visualization panels (Bottom Left and Right). The Bottom Left panel shows the task-fMRI activation overlays (t > 4.04, p < 10⁻⁴, uncorrected) on a high-resolution T₁w image using the warm color map. The result of CVR mapping (t > 2.65, p < 0.01, uncorrected) displays as transparent blue with a solid blue contour. The area outside the CVR map, but inside potential functional anatomy near the lesion, indicates the location of possible NVU. The Bottom Right panel shows the CVR map using a warm color map.