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. 2018 Mar 9;12:11. doi: 10.3389/fninf.2018.00011

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Copyright © 2018 Hsu, Hou, Johnson, Wu, Noll, Prabhu, Ferguson, Kumar, Schomer, Hazle, Chen and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Language mapping of rs-fMRI with seed guided by RH+MA map for Patient #2. (A) The RH+MA map with a ReHo threshold of 0.3 is overlaid on the T₁w image. (B,C) Seeding at a local maximum of ReHo value (blue circle), the rs-FC map above the Fisher's z threshold of 0.9 is overlaid on the T₁w and T₂w FLAIR image. (D) The thresholded rs-FC map overlaid on the T₁w image in the gray-scale DICOM format. (E) The rs-fMRI result analyzed independently from the IClinfMRI by using the procedure adopted in the previous study (Hart et al., 2016).