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. 2017 Sep 13;43(5):1156–1163. doi: 10.1038/npp.2017.169

Figure 1.

Figure 1

Anxiolytic effect of NPS infusion (0.2 nmol/0.5 μl) bilaterally into the MeA of male rats as assessed on the EPM (a–c) and the OF (d–f). During the 5 min of testing on the EPM, (a) the percentage of time spent on the EPM, (b) the percentage of entries into the open arms, and (c) number of closed arm entries were monitored. During the 5 min of testing in the OF, (d) the time spent in the OF, (e) the entries into the center zone, and (f) traveled distance were analyzed. Data represent mean+SEM, *p<0.05, **p<0.01 vs Veh; group sizes: n=7–9; except outsider n=2. (g) Schematic drawing of the MeA in gray (opt: optic tract, 3V: third ventricle, Paxinos and Watson, 1998) and (h) representative microphotographs of bilateral MeA infusion sites in a coronal brain slice (H1 and H2). H3 represents an infusion site considered as outsider.