Table 2. Comparison of clinical and laboratory variables between the Kawasaki disease with adenoviral infection group and the adenoviral infection group.
| Variable | KD with adenovirus (n=11) | Isolated adenoviral infection (n=147) | P value |
|---|---|---|---|
| Age (mo) | 36.0 (29.5–42.2) | 32.1 (20.2–39.3) | 0.512 |
| Male sex | 6 (54.5) | 83 (56.5) | 0.690 |
| Body weight (kg) | 15.5 (14.1–17.2) | 13.1 (11.6–15.9) | 0.351 |
| Total fever duration (day) | 6 (5.0–6.5) | 6 (4.9–6.6) | 0.356 |
| Conjunctival injection | 11 (100) | 110 (74.8) | 0.067 |
| Lip and tongue change | 9 (81.8) | 23 (15.6) | <0.001* |
| Skin rash | 8 (72.7) | 54 (36.7) | 0.007* |
| Cervical lymphadenitis | 9 (81.8) | 78 (53.1) | 0.084 |
| Changes in extremities | 7 (63.6) | 15 (10.2) | 0.001* |
| Total white blood cell count (×103/µL) | 10.5 (8.4–19.5) | 11.7 (9.1–14.8) | 0.773 |
| Neutrophil count (×103/µL) | 7.2 (4.4–17.3) | 6.8 (5.6–9.7) | 0.071 |
| Neutrophil/lymphocyte ratio | 4.6 (2.7–6.3) | 2.6 (1.7–5.6) | 0.053 |
| Anemia for age | 6 (54.5) | 45 (30.6) | 0.102 |
| Erythrocyte sedimentation rate (mm/hr) | 45 (33.2–56.4) | 32.5 (21.6–41.2) | 0.077 |
| C-reactive protein (mg/L) | 67.5 (58.5–78.1) | 31.9 (19.2–48.1) | 0.002* |
| Lactate dehydrogenase (IU/L) | 284.1 (250.5–325.3) | 317.5 (273.3–357.5) | 0.083 |
| B-type natriuretic peptide (pg/mL) | 59.6 (45.5 –105.2) | NA | NA |
| Hyponatremia | 2 (18.2) | 15 (10.2) | 0.436 |
| Hypoalbuminemia | 1 (9.1) | 1 (0.7) | 0.009* |
| AST/ALT elevation | 3 (27.3) | 15 (10.2) | 0.334 |
| Sterile pyuria | 6 (54.5) | 16 (10.9) | 0.001* |
Values are presented as median (interquartile range) or number (%)
KD, Kawasaki disease; AST, aspartate aminotransferase; ALT, alanine aminotransferase; NA, not available.
*P<0.05