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. 2018 Jan 19;131(10):1111–1121. doi: 10.1182/blood-2017-08-802918

Figure 4.

Figure 4.

Merozoites invasion with or without HP6H8 treatment. (A) Timeline of the merozoite invasion process in this study. (B) The development of merozoites during invasion in normal conditions observed with a TEM. Scale bar, 500 nm. (C) Merozoite invasion after HP6H8 treatment observed with a TEM. Scale bar, 500 nm. (D) Model of key receptors and ligands participating in the invasion process. (Black arrow) HP6H8 stopped PV formation by blocking the interaction between CD147 and RAP2.