Figure 1.

Isolated first trimester DSC expression of the decidual markers IGFBP1 and PRL. Isolated DSC were stimulated with cAMP and MPA (re-decidualised, rDSC) or a vehicle control (DSC) for 72 h. Conditioned media was collected and levels of decidual markers IGFBP1 and PRL measured by ELISA. Secretion of (A) IGFBP1 (n = 53) and (B) PRL (n = 40) was found to be significantly different between DSC and rDSC. Data were log-transformed to ensure equal variance. Paired t-test, data shown as mean ± s.e.m., ****P < 0.0001.