Table 2. Clinical and biochemical features of non-obese polycystic ovary syndrome (PCOS) patients with and without hyperandrogenism.
| Parameters | Hyperandrogenic PCOS (n=41) | Non-hyperandrogenic PCOS (n=33) | P-value | |
|---|---|---|---|---|
| Metabolic parameters | ||||
| Age (yr) | 23.7±5.5 | 23.9±5.5 | 0.861 | |
| BMI (kg/m2) | 20.7±2.2 | 20.1±1.9 | 0.164 | |
| WC (cm) | 67.4±5.6 | 66.6±5.5 | 0.566 | |
| Hirsutism score | 6.5 (1–9) | 3 (0–5) | <0.001 | |
| Systolic BP (mmHg) | 113.7±13.5 | 113.0±9.5 | 0.767 | |
| Diastolic BP (mmHg) | 75.3±6.8 | 75.4±6.3 | 0.963 | |
| Fasting glucose (mg/dL) | 84.3±6.8 | 85.6±5.2 | 0.385 | |
| HOMA-IR | 1.78 (1.48–2.16) | 1.79 (1.47–2.16) | 0.996 | |
| 75 g OGTT glucose | 92.2±16.6 | 97.7±20.9 | 0.221 | |
| 75 g OGTT insulin | 44.4 (36.6–53.9) | 38.9 (30.5–49.5) | 0.380 | |
| Total cholesterol (mg/dL) | 176.0±27.1 | 174.9±30.0 | 0.868 | |
| Triglyceride (mg/dL) | 83.4±38.4 | 79.3±29.1 | 0.621 | |
| HDL cholesterol (mg/dL) | 65.1±15.8 | 66.7±17.7 | 0.683 | |
| LDL cholesterol (mg/dL) | 94.3±21.4 | 94.8±24.5 | 0.929 | |
| Hemoglobin A1c (%) | 5.41±0.90 | 5.36±0.27 | <0.001 | |
| Uric acid (mg/dL) | 4.77±1.11 | 4.45±0.66 | 0.172 | |
| Hormonal parameters | ||||
| Total testosterone (ng/mL) | 0.43 (0.36–0.50) | 0.32 (0.28–0.36) | 0.006 | |
| Free testosterone (pg/mL) | 1.05 (0.90–1.22) | 0.76 (0.64–0.91) | 0.006 | |
| SHBG (nmol/L) | 44.4 (36.6–53.9) | 55.3 (47.2–64.8) | 0.090 | |
| FAI | 3.31 (2.55–4.30) | 1.98 (1.66–2.37) | 0.003 | |
| Luteinizing hormone (IU/L) | 8.4 (6.0–11.9) | 8.6 (6.0–12.4) | 0.978 | |
| Follicle stimulating hormone (IU/L) | 5.0 (4.1–6.0) | 5.4 (4.4–6.6) | 0.557 | |
| Estradiol (pg/mL) | 34.3 (24.5–47.8) | 26.9 (19.2–37.7) | 0.308 | |
| Visfatin (ng/mL) | 3.87 (3.09–4.85) | 2.69 (2.06–3.52) | 0.038 | |
Data are shown as the means±standard deviation, median (interquartile range), or geometric mean (95% confidence intervals). P-values are indicated for the differences between groups, as analyzed using a Student's t-test.
BMI, body mass index; WC, waist circumference; BP, blood pressure; HOMA-IR, homeostasis model assessment of insulin resistance; OGTT, oral glucose tolerance test; HDL, high-density lipoprotein; LDL, low-density lipoprotein; SHBG, sex hormone binding globulin; FAI, free androgen index.