Table 1.
Body weight of dams | Treatment during pregnancy | ||
---|---|---|---|
Control | Pair-fed | Alcohol-exposed | |
Pregnant dams (N) | 10 | 11 | 13 |
Maternal death/illness (N) | 0 | 0 | 0 |
Perinatal death | 0.4 ± 0.2 | 0.36 ± 0.2 | 0.38 ± 0.2 |
Litter size | 15.8 ± 0.8 | 14.7 ± 0.8 | 15.2 ± 0.7 |
Total litter mass | 104.8 ± 4.4 | 101.3 ± 4.1 | 97.9 ± 3.8 |
DAM WEIGHT (g) | |||
GD 1 | 287.1 ± 3.5 | 289.3 ± 3.5 | 289.5 ± 3.1 |
GD 7 | 331.5 ± 4.2 | 307.5 ± 4.2a | 305.8 ± 3.7a |
GD 14 | 387.8 ± 6.4 | 354.5 ± 6.4a | 347.5 ± 5.6a |
GD 21 | 497.0 ± 9.2 | 445.0 ± 9.2a | 434.8 ± 8.1a |
LD 1 | 393.6 ± 7.5 | 367.0 ± 7.2a | 349.0 ± 6.6a |
LD 8 | 381.4 ± 7.4 | 369.1 ± 7.1 | 374.3 ± 6.5 |
LD 15 | 378.8 ± 7.4 | 368.5 ± 7.0 | 381.4 ± 6.5 |
LD 22 | 347.4 ± 6.0 | 336.3 ± 5.7 | 350.8 ± 5.3 |
Body weight of offspring | Prenatal treatment | ||
Control | Pair-fed | PAE | |
MALES | |||
PND 1 | 6.9 ± 0.2 | 7.1 ± 0.2 | 6.6 ± 0.2 |
PND 8 | 17.7 ± 0.6 | 18.7 ± 0.6 | 18.0 ± 0.5 |
PND 15 | 33.9 ± 2.0 | 35.3 ± 1.9 | 33.9 ± 1.8 |
PND 22 | 56.1 ± 1.5 | 57.5 ± 1.4 | 59.3 ± 1.3 |
Pre-CUS | 548.3 ± 11.2 | 553.8 ± 11.2 | 561.4 ± 11.2 |
FEMALES | |||
PND 1 | 6.7 ± 0.1 | 6.8 ± 0.1 | 6.4 ± 0.1 |
PND 8 | 17.1 ± 0.5 | 17.7 ± 0.5 | 17.4 ± 0.5 |
PND 15 | 33.0 ± 1.3 | 34.2 ± 1.2 | 35.2 ± 1.1 |
PND 22 | 54.9 ± 1.5 | 55.7 ± 1.4 | 56.7 ± 1.3 |
Pre-CUS | 314.2 ± 6.5 | 311.1 ± 6.5 | 337.5 ± 6.5b |
PAE = PF < C.
PAE > C = PF.