Figure 1.

Workflow of thermographic image assessment and analysis of children with hemophilia (left) and example images for a termographic overview and close up images (right). After adaption period of 20 min to ambient temperature, thermograms of the individual anatomic points were assessed in front and rear view (right). According to anatomic reference points, right/left differences were calculated and correlated to clinical examination. Afterwards a confusion matrix was used to assess the accuracy, specificity and sensitivity of thermography compared to clinical examination.