Table 1.

Search terms and number of articles found from a preliminary PubMed search

Step	Searching terms	Articles found (n)*
#1	“Quantitative Trait, Heritable” [MeSH] OR “Endophenotypes”[MeSH] OR Heritab*[tiab]	36 287
#2	Glaucoma[MeSH] OR Glaucoma*[tiab]	62 936
#3	Normal tension glaucoma[MeSH] OR Low tension glaucoma[MeSH] OR Exfoliation Glaucoma[MeSH] OR pseudoexfoliation glaucoma[MeSH] OR Exfoliation Syndrome[MeSH] OR Pigment dispersion syndrome[MeSH] OR Pigment dispersion syndrome[tiab] OR pds[tiab] OR Congenital glaucoma [MeSH] OR Buphthalmos[tiab] OR Buphthalmus[tiab] OR “Juvenile glaucoma”[tiab]	19 552
#4	“Intraocular pressure”[tiab] OR ‘“Ocular pressure”[tiab] OR iop[tiab] OR “Ocular hypertension”[tiab] OR “ocular biometric”[tiab] OR “Central corneal thickness”[tiab] OR “Corneal shape”[tiab] OR “Axial length”[tiab] OR Linear cup-disc ratio OR lcdr OR “Vertical cup to disc ratio”[tiab] OR Vertical cup-to-disc ratio[tiab] OR vcdr[tiab] OR vertical cup:disc ratio[tiab] OR vertical cup-disc ratio[tiab] OR “Corneal hysteresis”[tiab] OR “Anterior chamber depth”[tiab] OR “Anterior chamber angle” OR “Narrow anterior chamber” OR “Optic disc diameter”[tiab] OR “Cup area”[tiab] OR “Disc area”[tiab] OR “Rim area”[tiab] OR “Retinal nerve fibre layer”[tiab] OR “Cilioretinal arteries”[tiab] OR “Retinal ganglion cell layer” OR Horizontal cup:disc ratio[tiab] OR “Disc diameter”[tiab] OR “Cup disc ratio”[tiab] OR “Ganglion cell complex thickness”[tiab] OR “Shallow anterior chamber”[tiab] OR “Iris thickness”[tiab] OR “Iris area”[tiab] OR “Plateau iris” OR “Pupil diameter”[tiab] OR “Pupil size”[tiab] OR “Iridotrabecular angle width”[tiab] OR “Bruch’s membrane opening” OR “Neuroretinal rim” OR Excavation[tiab] OR Cupping[tiab] OR “Inner plexiform layer thickness”[tiab] OR “angle opening” distance”[tiab] OR aod[tiab] OR “trabecular iris space area” OR tisa[tiab] OR “angle recess area”[tiab] OR ara [tiab]	62 213
#5	#2 OR #3 OR #4	106 800
#6	#1 AND #5	194

*Preliminary search conducted on 14 December 2017 at 07:20:51.

MeSH, Medical Subject Heading; tiab, title abstract text.