Table 5.

Rates and RRs of invasive pneumococcal disease in the MDV database

	All ages (≥19 years)		Age subgroups
			19–49 years		50–64 years		≥65 years
	Rate*	RR† (95% CI)	Rate*	RR‡ (95% CI)	Rate*	RR‡ (95% CI)	Rate§	RR‡ (95% CI)
Overall	4.6		1.5		3.8		5.9
Risk status
Healthy (no condition)	1.9	1.0	0.9	1.0	0.9	1.0	3.0	1.0
At-risk conditions	8.0	3.8 (2.4 to 6.2)	4.0	4.0 (0.9 to 18.4)	7.7	9.2 (2.7 to 31.1)	8.7	3.0 (1.7 to 5.1)
High-risk conditions	8.6	4.0 (2.4 to 6.7)	4.2	4.7 (0.8 to 28.1)	8.6	9.8 (2.8 to 34.7)	9.2	3.1 (1.7 to 5.6)
Medical condition§
No condition	1.9	1.0	0.9	1.0	0.9	1.0	3.0	1.0
Chronic heart disease	9.3	4.7 (2.8 to 7.9)	17.7	18.4 (4.0 to 84.2)	6.4	8.0 (2.0 to 32.0)	9.6	3.3 (1.8 to 5.8)
Chronic lung disease	13.8	7.1 (4.2 to 12.0)	5.9	6.5 (1.1 to 39.0)	18.4	21.4 (5.9 to 77.8)	13.8	4.7 (2.5 to 8.7)
Diabetes mellitus	8.5	4.4 (2.6 to 7.3)	10.7	11.0 (2.4 to 50.6)	8.5	10.4 (2.9 to 37.2)	8.3	2.8 (1.6 to 5.2)
Chronic liver disease	8.9	4.7 (2.7 to 8.2)	5.7	5.9 (1.0 to 36.1)	5.8	6.9 (1.6 to 28.9)	11.1	3.8 (2.0 to 7.2)
Chronic renal disease	9.1	4.7 (2.2 to 10.0)	0	0	12.6	15.4 (3.1 to 76.8)	9.3	3.2 (1.3 to 7.7)
Cancer	8.6	4.4 (2.6 to 7.4)	5.3	6.0 (1.0 to 36.2)	7.6	8.6 (2.3 to 31.9)	9.3	3.2 (1.8 to 5.9)
Number of conditions
0	1.9	1.0	0.9	1.0	0.9	1.0	3.0	1.0
1	3.1	1.6 (0.9 to 2.8)	0	0	2.8	3.3 (0.8 to 13.4)	4.0	1.4 (0.7 to 2.7)
≥2	12.1	5.8 (3.6 to 9.5)	11.6	11.6 (2.5 to 54.0)	12.9	16.2 (4.7 to 55.7)	11.9	4.1 (2.3 to 7.1)

*Per 100 000 person-years.

†Age-adjusted and sex-adjusted RR.

‡Sex-adjusted RR.

§Results of subgroups with other medical conditions, including HIV/AIDS, alcoholism, asplenia, organ transplantation and cerebrospinal fluid leakage, are not shown.

MDV, Medical Data Vision; RR, rate ratio.