Figure 4.

A reminder reinstates the apparently forgotten nOL memory. Experimental schedule is shown above the panels. Rats were handled, habituated to the arena and trained in nOL at PN17 (trained, white bar), or handled, habituated but left in their homecage during the training session (control, gray bar). (A–C) Percent exploration time of the moved object during: (A) training at PN17, (B) reminder at PN20, and (C) test 1 min thereafter. (D–F) Total exploration time (in seconds, sec) for both familiar and moved object at: (D) training, (E) reminder at PN20, and (F) test 1 min thereafter. Data are expressed as means ± SEM (n = 7–8 per group). (*) P < 0.05 significance for unpaired two-tailed Student's t-test comparing PN17 trained with PN17 control. (###) P < 0.001 significance for one sample t-tests comparing each group to chance performance (50%).