Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Calculated average enthalpy (H), entropy (TS) and Gibbs free energy (G) values for the WT, A53T mutant, A30 P mutant and E46 K mutant type αS proteins in an aqueous solution medium.
| Protein | <H> (kJ·mol−1) | −T<SNMA> (kJ·mol−1) | <GMM/PBSA> (kJ·mol−1) |
|---|---|---|---|
| WT αS | −9557.4 (±18.4) | −7043.8 (±8.4) | −16,601.4 (±13.0) |
| A53T αS | −9662.3 (±21.0) | −7072.0 (±9.6) | −16,734.3 (±10.2) |
| A30P αS | −9461.4 (±50.8) | −7057.3 (±18.8) | −16,518.7 (±32.1) |
| E46K αS | −9495.6 (±60.9) | −6991.3 (±13.7) | −16,486.9 (±54.2) |
