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. 2018 Jan 25;19(2):354. doi: 10.3390/ijms19020354

Figure 4.

Figure 4

MWCNT functionalization effects autophagy as seen by GFP LC3 detection following particle instillation. One-day particle instillation of 50 μg indicated by dark bars. The seven-day instillation of 50 μg indicated by white bars. Data are expressed as mean ± SEM percent macrophages expressing LC3 green fluorescent protein, which indicates the presence of autophagic activity. Functionalization of 38.4 is 5 min of processing and 15.7 is 60 min of processing. Daggers †† indicate significance at p < 0.01, or † indicating significance at p < 0.05 compared to corresponding DM vehicle negative controls. Asterisks ** indicate significance at p < 0.01, or * indicating significance at p < 0.05 compared to corresponding MWCNT source controls. n = 3–4 mice per group.