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. 2018 Jan 31;19(2):419. doi: 10.3390/ijms19020419

Figure 2.

Figure 2

Effect of SAHA treatment on SERCA2 ATPase activity evaluated in cardiomyocytes isolated from adult rat hearts and HL-1 cells. (a) ATPase activity assay performed on microsomes isolated from adult rat CMs either untreated or treated with SAHA at pCa5. Experiments were performed on 3 independent CM sets per group and repeated twice. Unpaired Student’s t-test: * p < 0.005 vs. CTR; (b) ATPase activity assay performed on microsomes isolated from HL-1 cells at different pCa. Each point represents the mean ± SEM of at least 4 independent experiments; Two-way ANOVA followed by Sidak’s multiple comparison: * p < 0.05 vs. SAHA pCa6; # p < 0.05 vs. SAHA pCa5. All data are presented as mean ± SEM.