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. 2018 Feb 2;19(2):448. doi: 10.3390/ijms19020448

Table 1.

Summary of plant-derived compounds and their mechanism for inducing apoptosis.

Compound Found in Mechanism
Aloe-emodin Rheum palmatum Induces cytochrome c release [32]
Black cohosh Actaea racemosa Activates caspases [28]
Curcumin Tumeric Inhibits BCL-2 and XIAP [33]
Epigallocatechin-3-gallate Green tea component Activates cell death receptors [34]
Genistein Soybeans Cell cycle arrest activation [35]
Graviola Annona muricata Inhibits BCL-2 and activates BAX [26]
Juglone Juglans mandshurica Increase caspase 9 cleavage [36]
Quercetin Bark of many plants Modulating cell cycle regulators to arrest the cell cycle [37]