Table 1.
Genes considered for T cell pathways in the study and their numbers of cytosine–phosphate–guanine (CpG) sites.
| Pathway | Number of Genes | Genes Coding Cytokines, Proteins, or Receptors | Number of CpG Sites |
|---|---|---|---|
| Th1 | 19 |
IFN-γ family [12,13,14,15,16,17,18,19,20,21,22,23] TNF-α family [12,13,14,15,16,17,18,19,20,21,22,23] IL-2 [12,13,14,17,20,22,23] IL-12 family [13,18,24] |
155 |
| Th2 | 12 |
IL-4 [12,13,15,16,17,18,19,20,22,26,27,28,29,30,31,32] IL4R [29,32,33] IL-5 5 [12,13,16,17,18,19,20,22,23,26,27] IL-9 [17,20,22] IL-13 family [12,13,16,17,18,19,20,22,23,25,26,27,29,31,34] GATA3 [23,29] STAT6 [18,23,29,31,32,34] JAK1 [35] JAK3 [32,33,35] IL1RL1 [12,19,22] |
77 |
| Th17 | 15 |
IL17 family [12,19,22] IL21 family [22,36] IL22 family [19,22] |
106 |
| Treg | 2 |
FOXP3 [37,38] CTLA4 [39] |
10 |