Table 7.
Number and proportion of CpG sites according to their position on the gene.
| Position of CpGs on Gene a | Th1, Th2, Th17 and Treg Gene CpGs (Total 348) n (%) | Random CpGs from Whole Genome (Total 3480) n (%) | Random CpGs from Genes Expressed in CD4+ Cells (Total 3480) n (%) | Random CpGs from Whole Genome Excluding CpGs Situated in Intergenic Region (Total 348) n (%) |
|---|---|---|---|---|
| Body, 3′UTR, and Promoter | 0 (0) | 1 (0.03) | 0 (0) | 1 (0.03) |
| Body, 5′UTR, and Promoter | 6 (1.7) | 33 (1.0) | 74 (2.1) | 37 (1.1) |
| Body and 3′UTR | 3 (0.9) | 23 (0.7) | 26 (0.8) | 34 (1.0) |
| Body and 5′UTR | 21 (6.0) | 148 (4.3) | 197 (5.7) | 180 (5.2) |
| Body and Promoter | 4 (1.2) | 134 (3.9) | 293 (8.4) | 161 (4.6) |
| Body | 129 (37.1) | 1140 (32.8) | 1375 (39.5) | 1489 (42.8) |
| 3′UTR and Promoter | 1 (0.3) | 5 (0.1) | 15 (0.4) | 9 (0.1) |
| 5′UTR and Promoter | 8 (2.3) | 55 (1.6) | 116 (3.3) | 65 (1.9) |
| Promoter | 117 (33.6) | 854 (24.5) | 1005 (28.9) | 1114 (32.0) |
| 3′UTR and 5′UTR | 0 (0) | 0 (0) | 1 (0.03) | 0 (0) |
| 3′UTR | 26 (7.5) | 124 (3.6) | 149 (4.1) | 153 (4.4) |
| 5′UTR | 33 (9.5) | 200 (5.7) | 229 (6.6) | 237 (6.8) |
| Intergenic | 0 (0) | 763 (21.9) | 0 (0) | 0 (0) |
a Body = Body and/or 1st Exon; Promoter = TSS (transcription start site).