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. 2018 Feb 8;19(2):508. doi: 10.3390/ijms19020508

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of voluntary exercise on gait analysis in animals exposed to 6-OHDA. Using twelve parameters to determine the gait disturbance changes in animals after administration of 6-OHDA, which induced unilateral nigrostriatal dopamine depletion. Walking speed (A); base of support (BOS) (B); left step length (LStepL) (C); right step length (RStepL) (D); left stride length (LStrideL) (E); right stride length (RStrideL) (F); left print length (LPL) (G); right print length (RPL) (H); left foot angle (LFtAng) (I); right foot angle (RFtAng) (J). Values were expressed as mean ± SEM (Non-Ex, n = 15; Exercise, n = 12) and compared with the pre 6-OHDA lesion (PRE) or non-exercise (Non-Ex) group. All analyses based on two way ANOVA, * p < 0.05; ** p < 0.01; *** p < 0.001.