Table 1.

Summary of the relevant DNA methylation of genes associated with radiotherapy/response in various cancers.

Cancer Types	Gene Names	Methylation Status	Response to RT	Irradiation Induced Methylation Alteration	Prognostic Marker of Cancer	Reference
Glioblastoma multiforme	MGMT	Hyper	Sensitive		●	[43,44,45]
Lung cancer	CDKN2A	Hyper	Resistant	Hyper		[46,47]
	SERPINB5 & S100A6	Hyper	Resistant			[48]
	CAT & BNCI	Hypo
Esophageal cancer	CDKN2A, RPRM, CDKN1C, TP73, RUNX3, CHFR, MGMT, TIMP3 & HPP1	Hypo	Sensitive		●
					●	[49,50]
Cervical cancer	TP73	Hyper	Resistant			[51]
Head and Neck squamous cell carcinoma	TIMP3 & CDH1	Hyper	Sensitive		●	[52]
	IRX1, EBF3, SLC5A8 & FUSSEL18			Hyper		[40]
	CCND2	Hyper	Resistant			[53]
Nasopharyngeal carcinoma	miR-24 & FHIT	Hyper	Resistant			[54]
			Resistant		●	[55]
Laryngeal cancer	TOPO2A, PLXDC2, ETNK2, GFI1 & IL12B	Hyper	Resistant			[43]
Breast cancer	ADAMTS9, FOXC1 & TRAPPC9			Hyper		[39]
	AMIGO3			Hypo
	AGAP1, ARHGEF10, ATP11A, HDAC4, PTPRD, PRR4 & TBCD			Hyper		[33]

●: determined; RT: radiotherapy.