Table 1.
Cancer Types | Gene Names | Methylation Status | Response to RT | Irradiation Induced Methylation Alteration | Prognostic Marker of Cancer | Reference |
---|---|---|---|---|---|---|
Glioblastoma multiforme | MGMT | Hyper | Sensitive | ● | [43,44,45] | |
Lung cancer | CDKN2A | Hyper | Resistant | Hyper | [46,47] | |
SERPINB5 & S100A6 | Hyper | Resistant | [48] | |||
CAT & BNCI | Hypo | |||||
Esophageal cancer | CDKN2A, RPRM, CDKN1C, TP73, RUNX3, CHFR, MGMT, TIMP3 & HPP1 | Hypo | Sensitive | ● | ||
● | [49,50] | |||||
Cervical cancer | TP73 | Hyper | Resistant | [51] | ||
Head and Neck squamous cell carcinoma | TIMP3 & CDH1 | Hyper | Sensitive | ● | [52] | |
IRX1, EBF3, SLC5A8 & FUSSEL18 | Hyper | [40] | ||||
CCND2 | Hyper | Resistant | [53] | |||
Nasopharyngeal carcinoma | miR-24 & FHIT | Hyper | Resistant | [54] | ||
Resistant | ● | [55] | ||||
Laryngeal cancer | TOPO2A, PLXDC2, ETNK2, GFI1 & IL12B | Hyper | Resistant | [43] | ||
Breast cancer | ADAMTS9, FOXC1 & TRAPPC9 | Hyper | [39] | |||
AMIGO3 | Hypo | |||||
AGAP1, ARHGEF10, ATP11A, HDAC4, PTPRD, PRR4 & TBCD | Hyper | [33] |
●: determined; RT: radiotherapy.