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Ultrastructural characteristics of melanosome stages.
| Stage | Criteria |
|---|---|
| I | Spherical, no melanin, presence of a planar clathrin coat, and few intraluminal vesicles |
| II | Oval, no melanin, presence of internal fibrils |
| III | Oval, moderate deposits of melanin onto internal fibrils |
| IV | Oval, intense deposits of melanin onto internal fibrils |
