Figure 2.

B-cell differentiation subsets in patients with obstetric and thrombotic primary antiphospholipid syndrome (pAPS). Percentages of transitional-immature (CD19⁺CD5⁺CD10⁺ CD27⁻IgD⁺⁺ CD24^hi CD38^hi), naïve (CD19⁺ CD5^+/− CD10⁻ CD27⁻IgD⁺ CD24^int CD38^low/⁻), and non-switched memory (CD19⁺ CD27⁺IgD⁺ CD38⁻IgM⁺) B cells in patients subdivided into obstetric and thrombotic pAPS and compared to HC and SLE. Box plots show the median and interquartile range. Differences were significant when p value <0.05 by Mann–Whitney U test. Abbreviations: HC, healthy controls; pAPS, primary antiphospholipid syndrome; SLE, systemic lupus erythematosus.